DRUG TRANSPORT IN THE LIVER - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 403

205. Silva VM, Thibodeau MS, Chen C, Manautou JE. 2005. Transport deficient (TR-) hy-
perbilirubinemic rats are resistant to acetaminophen hepatotoxicity. Biochem Pharmacol
70(12):1832-1839.
206. Gao B, Hagenbuch B, Kullak-Ublick GA, Benke D, Aguzzi A, Meier PJ. 2000. Organic
anion-transporting polypeptides mediate transport of opioid peptides across blood-brain
barrier. J Pharmacol Exp Ther 294(1):73-79.
207. Kubitz R, Sutfels G, Kuhlkamp T, Kolling R, Haussinger D. 2004. Trafficking of the bile
salt export pump from the Golgi to the canalicular membrane is regulated by the p38
MAP kinase. Gastroenterology 126(2):541-553.
208. Kameyama Y, Yamashita K, Kobayashi K, Hosokawa M, Chiba K. 2005. Functional
characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and
SLCO1B1*15 + C1007G, by using transient expression systems of HeLa and HEK293
cells. Pharmacogenet Genom 15(7):513-522.
209. Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A. 2000. Molec-
ular identification and characterization of novel members of the human organic

anion transporter (OATP) family. Biochem Biophys Res Commun 273(1):251-

260.
210. Sandhu P, Lee W, Xu X, Leake BF, Yamazaki M, Stone JA, Lin JH, Pearson PG, Kim
RB. 2005. Hepatic uptake of the novel antifungal agent caspofungin. Drug Metab Dispos
33(5):676-682.
211. Nozawa T, Minami H, Sugiura S, Tsuji A, Tamai I. 2005. Role of organic anion
transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite,
7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide
polymorphisms. Drug Metab Dispos 33(3):434-439.
212. Meier-Abt F, Faulstich H, Hagenbuch B. 2004. Identification of phalloidin uptake
systems of rat and human liver. Biochim Biophys Acta 1664(1):64-69.
213. Fujino H, Nakai D, Nakagomi R, Saito M, Tokui T, Kojima J. 2004. Metabolic stability
and uptake by human hepatocytes of pitavastatin, a new inhibitor of HMG-CoA
reductase. Arzneimittelforschung 54(7):382-388.
214. Hirano M, Maeda K, Shitara Y, Sugiyama Y. 2004. Contribution of OATP2 (OATP1B1)
and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J Pharmacol
Exp Ther 311(1):139-146.
215. Nakai D, Nakagomi R, Furuta Y, Tokui T, Abe T, Ikeda T, Nishimura K. 2001. Human
liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human
hepatocytes. J Pharmacol Exp Ther 297(3):861-867.
216. Vavricka SR, van Montfoort J, Ha HR, Meier PJ, Fattinger K. 2002. Interactions
of rifamycin SV and rifampicin with organic anion uptake systems of human liver.
Hepatology 36(1):164-172.
217. Nozawa T, Sugiura S, Nakajima M, Goto A, Yokoi T, Nezu J, Tsuji A, Tamai I. 2004.
Involvement of organic anion transporting polypeptides in the transport of troglitazone
sulfate: implications for understanding troglitazone hepatotoxicity. Drug Metab Dispos
32(3):291-294.
218. Ismair MG, Stieger B, Cattori V, Hagenbuch B, Fried M, Meier PJ, Kullak-Ublick
GA. 2001. Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting
polypeptides OATP4 and OATP8 of rat and human liver. Gastroenterology 121(5):1185-
1190.