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are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to
ABC transport genes. Cancer Res 59:8-13.
13. Dean, M, Rzhetsky, A, and Allikmets, R. 2001. The human ATP-binding cassette (ABC)
transporter superfamily. Genome Res 11:1156-1166.
14. Wang, N, Lan, D, Chen, W, Matsuura, F, and Tall, AR. 2004. ATP-binding cassette
transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.
Proc Natl Acad SciUSA101:9774-9779.
15. Mickley, L, Jain, P, Miyake, K, Schriml, LM, Rao, K, Fojo, T, Bates, S, and Dean, M.
2001. An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter
ABCG2 (MXR/ABCP) has an unusual ATP-binding domain. Mamm Genome 12:86-88.
16. Yu, L, Li-Hawkins, J, Hammer, RE, Berge, KE, Horton, JD, Cohen, JC, and Hobbs, HH.
2002. Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and
reduces fractional absorption of dietary cholesterol. J Clin Invest 110:671-680.
17. Bailey-Dell, KJ, Hassel, B, Doyle, LA, and Ross, DD. 2001. Promoter characterization
and genomic organization of the human breast cancer resistance protein (ATP-binding
cassette transporter G2) gene. Biochim Biophys Acta 1520:234-241.
18. Knutsen, T, Rao, VK, Ried, T, Mickley, L, Schneider, E, Miyake, K, Ghadimi, BM,
Padilla-Nash, H, Pack, S, Greenberger, L, et al. 2000. Amplification of 4q21-q22 and the
MXR gene in independently derived mitoxantrone-resistant cell lines. Genes Chromo-
somes Cancer 27:110-116.
19. Rao, VK, Wangsa, D, Robey, RW, Huff, L, Honjo, Y, Hung, J, Knutsen, T, Ried, T, and
Bates, SE. 2005. Characterization of ABCG2 gene amplification manifesting as extra-
chromosomal DNA in mitoxantrone-selected SF295 human glioblastoma cells. Cancer
Genet Cytogenet 160:126-133.
20. Berkower, C, and Michaelis, S. 1991. Mutational analysis of the yeast a-factor trans-
porter STE6, a member of the ATP binding cassette (ABC) protein superfamily. EMBO
J 10:3777-3785.
21. Graf, GA, Yu, L, Li, WP, Gerard, R, Tuma, PL, Cohen, JC, and Hobbs, HH. 2003. ABCG5
and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol ex-
cretion. J Biol Chem 278:48275-48282.
22. Bhatia, A, Schafer, HJ, and Hrycyna, CA. 2005. Oligomerization of the human ABC
transporter ABCG2: evaluation of the native protein and chimeric dimers. Biochemistry
44:10893-10904.
23. Henriksen, U, Gether, U, and Litman, T. 2005. Effect of Walker A mutation (K86M) on
oligomerization and surface targeting of the multidrug resistance transporter ABCG2. J
Cell Sci 118:1417-1426.
24. Kage, K, Tsukahara, S, Sugiyama, T, Asada, S, Ishikawa, E, Tsuruo, T, and Sugimoto,
Y. 2002. Dominant-negative inhibition of breast cancer resistance protein as drug efflux
pump through the inhibition of S-S dependent homodimerization. Int J Cancer 97:626-
630.
25. Chang, G, and Roth, CB. 2001. Structure of MsbA from E. coli : a homolog of the
multidrug resistance ATP binding cassette (ABC) transporters. Science 293:1793-1800.
26. Chang, G. 2003. Structure of MsbA from Vibrio cholera : a multidrug resistance ABC
transporter homolog in a closed conformation. J Mol Biol 330:419-430.
27. Reyes, CL, and Chang, G. 2005. Structure of the ABC transporter MsbA in complex with
ADP. vanadate and lipopolysaccharide. Science 308:1028-1031.
 
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