MULTIDRUG RESISTANCE PROTEINS OF THE ABCC SUBFAMILY - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 304

with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol 288:F327-
F333.
125. Smeets PH, van Aubel RA, Wouterse AC, van den Heuvel JJ, Russel FG. 2004. Con-
tribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p -
aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.
J Am Soc Nephrol 15:2828-2835.
126. Tian Q, Zhang J, Chan SY, Tan TM, Duan W, Huang M, Zhu YZ, Chan E, Yu Q, Nie YQ,
et al. 2006. Topotecan is a substrate for multidrug resistance associated protein 4. Curr
Drug Metab 7:105-118.
127. Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry W III, Dantzig AH.
2005. The multidrug resistance protein 5 (ABCC5) confers resistance to 5-
fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 4:855-
863.
128. Wielinga P, Hooijberg JH, Gunnarsdottir S, Kathmann I, Reid G, Zelcer N, van der
Born K, de Haas M, van der Heijden, I, Kaspers G, et al. 2005. The human multidrug
resistance protein MRP5 transports folates and can mediate cellular resistance against
antifolates. Cancer Res 65:4425-4430.
129. Chen ZS, Hopper-Borge E, Belinsky MG, Shchaveleva I, Kotova E, Kruh GD. 2003.
Characterization of the transport properties of human multidrug resistance protein 7
(MRP7, ABCC10). Mol Pharmacol 63:351-358.
130. Hopper-Borge E, Chen ZS, Shchaveleva I, Belinsky MG, Kruh GD. 2004. Analysis of
the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to
docetaxel. Cancer Res 64:4927-4930.
131. Guo Y, Kotova E, Chen ZS, Lee K, Hopper-Borge E, Belinsky MG, Kruh GD.
2003. MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux
pump and a resistance factor for fluoropyrimidines 2 ,3 -dideoxycytidine and 9 -(2 -
phosphonylmethoxyethyl)adenine. J Biol Chem 278:29509-29514.
132. Chen ZS, Guo Y, Belinsky MG, Kotova E, Kruh GD. 2005. Transport of bile acids, sul-
fated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug
resistance protein 8 (ABCC11). Mol Pharmacol 67:545-557.
133. Barrand MA, Rhodes T, Center MS, Twentyman PR. 1993. Chemosensitisation and drug
accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell
lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein. Eur
J Cancer 29A:408-415.
134. Norman BH, Dantzig AH, Kroin JS, Law KL, Tabas LB, Shepard RL, Palkowitz AD,
Hauser KL, Winter MA, Sluka JP, Starling JJ. 1999. Reversal of resistance in multidrug
resistance protein (MRP1)-overexpressing cells by LY329146. Bioorg Med Chem Lett
9:3381-3386.
135. Norman BH, Gruber JM, Hollinshead SP, Wilson JW, Starling JJ, Law KL, Self TD,
Tabas LB, Williams DC, Paul DC, Wagner MM, Dantzig AH. 2002. Tricyclic isoxazoles
are novel inhibitors of the multidrug resistance protein (MRP1). Bioorg Med Chem Lett
12:883-886.
136. Mao Q, Qiu W, Weigl KE, Lander PA, Tabas LB, Shepard RL, Dantzig AH, Deeley
RG, Cole SP. 2002. GSH-dependent photolabeling of multidrug resistance protein MRP1
(ABCC1) by [ 125 I]LY475776: evidence of a major binding site in the COOH-proximal
membrane spanning domain. J Biol Chem 277:28690-28699.