Biomedical Engineering Reference
In-Depth Information
4. Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. 1987.
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal
human tissues. Proc Natl Acad SciUSA84:7735-7738.
5. Croop JM, Raymond M, Haber D, Devault A, Arceci RJ, Gros P, Housman DE. 1989. The
three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner
in normal mouse tissues. Mol Cell Biol 9:1346-1350.
6. Beaulieu E, Demeule M, Ghitescu L, Beliveau R. 1997. P-glycoprotein is strongly ex-
pressed in the luminal membranes of the endothelium of blood vessels in the brain.
Biochem J 326:539-544.
7. Melaine N, Lienard MO, Dorval I, Le Goascogne C, Lejeune H, Jegou B. 2002. Multidrug
resistance genes and P-glycoprotein in the testis of the rat, mouse, guinea pig, and human.
Biol Reprod 67:1699-1707.
8. Edwards JE, Alcorn J, Savolainen J, Anderson BD, McNamara PJ. 2005. Role of P-
glycoprotein in distribution of nelfinavir across the blood-mammary tissue barrier and
blood-brain barrier. Antimicrob Agents Chemother 49:1626-1628.
9. Saito T, Zhang ZJ, Tsuzuki H, Ohtsubo T, Yamada T, Yamamoto T, Saito H. 1997.
Expression of P-glycoprotein in inner ear capillary endothelial cells of the guinea pig
with special reference to blood-inner ear barrier. Brain Res 767:388-392.
10. Arceci RJ, Croop JM, Horwitz SB, Housman D. 1988. The gene encoding multidrug
resistance is induced and expressed at high levels during pregnancy in the secretory
epithelium of the uterus. Proc Natl Acad SciUSA85:4350-4354.
11. Gil S, Saura R, Forestier F, Farinotti R. 2005. P-glycoprotein expression of the human
placenta during pregnancy. Placenta 26:268-270.
12. Kalabis GM, Kostaki A, Andrews MH, Petropoulos S, Gibb W, Matthews SG. 2005. Mul-
tidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection.
Biol Reprod 73:591-597.
13. Smit JJ, Schinkel AH, Mol CA, Majoor D, Mooi WJ, Jongsma AP, Lincke CR, Borst P.
1994. Tissue distribution of the human MDR3 P-glycoprotein. Lab Invest 71:638-649.
14. Schinkel AH. 1998. Pharmacological insights from P-glycoprotein knockout mice. Int J
Clin Pharmacol Ther 36:9-13.
15. Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, Mol CA,
van der Valk MA, Robanus-Maandag EC, Te RH. 1994. Disruption of the mouse mdr1a
P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased
sensitivity to drugs. Cell 77:491-502.
16. Jette L, Pouliot JF, Murphy GF, Beliveau R. 1995. Isoform I (mdr3) is the major form
of P-glycoprotein expressed in mouse brain capillaries: evidence for cross-reactivity of
antibody C219 with an unrelated protein. Biochem J 305:761-766.
17. Doran A, Obach RS, Smith BJ, Hosea NA, Becker S, Callegari E, Chen C, Chen X, Choo
E, Cianfrogna J, et al. 2005. The impact of P-glycoprotein on the disposition of drugs
targeted for indications of the central nervous system: evaluation using the MDR1A/1B
knockout mouse model. Drug Metab Dispos 33:165-174.
18. Roulet A, Puel O, Gesta S, Lepage JF, Drag M, Soll M, Alvinerie M, Pineau T. 2003.
MDR1-deficient genotype in collie dogs hypersensitive to the P-glycoprotein substrate
ivermectin. Eur J Pharmacol 460:85-91.
19. Nelson OL, Carsten E, Bentjen SA, Mealey KL. 2003. Ivermectin toxicity in an Australian
shepherd dog with the MDR1 mutation associated with ivermectin sensitivity in collies.
J Vet Intern Med 17:354-356.
Search WWH ::
Custom Search