NUCLEOSIDE TRANSPORTERS: CNTs AND ENTs - Drug Transporters: Molecular Characterization and Role in Drug Disposition - page 192

20. Crawford CR, Cass CE, Young JD, Belt JA. 1998. Stable expression of a recombinant
sodium-dependent, pyrimidine-selective nucleoside transporter (CNT1) in a transport-
deficient mouse leukemia cell line. Biochem Cell Biol 76(5):843-851.
21. Yao SY, Ng AM, Ritzel MW, Gati WP, Cass CE, Young JD. 1996. Transport of adenosine
by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from
rat jejunum expressed in Xenopus laevis oocytes. Mol Pharmacol 50(6):1529-1535.
22. Fang X, Parkinson FE, Mowles DA, Young JD, Cass CE. 1996. Functional character-
ization of a recombinant sodium-dependent nucleoside transporter with selectivity for
pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.
Biochem J 317(Pt 2):457-465.
23. Vickers MF, Young JD, Baldwin SA, Ellison MJ, Cass CE. 2001. Functional production
of mammalian concentrative nucleoside transporters in Saccharomyces cerevisiae . Mol
Membr Biol 18(1):73-79.
24. Mackey JR, Mani RS, Selner M, Mowles D, Young JD, Belt JA, Crawford CR, Cass
CE. 1998. Functional nucleoside transporters are required for gemcitabine influx and
manifestation of toxicity in cancer cell lines. Cancer Res 58(19):4349-4357.
25. Graham KA, Leithoff J, Coe IR, Mowles D, Mackey JR, Young JD, Cass CE. 2000.
Differential transport of cytosine-containing nucleosides by recombinant human concen-
trative nucleoside transporter protein hCNT1. Nucleosides Nucleotides Nucleic Acids
19(1-2):415-434.
26. Mata JF, Garcia-Manteiga JM, Lostao MP, Fernandez-Veledo S, Guillen-Gomez E,
Larrayoz IM, Lloberas J, Casado FJ, Pastor-Anglada M. 2001. Role of the human con-
centrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[prime]-deoxy-5-
fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer
drug. Mol Pharmacol 59(6):1542-1548.
27. Wang J, Schaner ME, Thomassen S, Su SF, Piquette-Miller M, Giacomini KM. 1997.
Functional and molecular characteristics of Na(+)-dependent nucleoside transporters.
Pharm Res 14(11):1524-1532.
28. Mackey JR, Yao SY, Smith KM, Karpinski E, Baldwin SA, Cass CE, Young JD. 1999.
Gemcitabine transport in Xenopus oocytes expressing recombinant plasma membrane
mammalian nucleoside transporters. J Natl Cancer Inst 91(21):1876-1881.
29. Che M, Ortiz DF, Arias IM. 1995. Primary structure and functional expression of a
cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter.
J Biol Chem 270(23):13596-13599.
30. Wang J, Su SF, Dresser MJ, Schaner ME, Washington CB, Giacomini KM. 1997. Na(+)-
dependent purine nucleoside transporter from human kidney: cloning and functional
characterization. Am J Physiol 273(6 Pt 2):F1058-F1065.
31. Ritzel MW, Yao SY, Ng AM, Mackey JR, Cass CE, Young JD. 1998. Molecular cloning,
functional expression and chromosomal localization of a cDNA encoding a human
Na + /nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine. Mol
Membr Biol 15(4):203-211.
32. Gerstin KM, Dresser MJ, Wang J, Giacomini KM. 2000. Molecular cloning of a Na + -
dependent nucleoside transporter from rabbit intestine. Pharm Res 17(8):906-910.
33. Patel DH, Crawford CR, Naeve CW, Belt JA. 2000. Cloning, genomic organization and
chromosomal localization of the gene encoding the murine sodium-dependent, purine-
selective, concentrative nucleoside transporter (CNT2). Gene 242(1-2):51-58.