Biomedical Engineering Reference
In-Depth Information
MONOCARBOXYLATE
TRANSPORTERS
JUSTIN A. SPANIER AND LESTER R. DREWES
University of Minnesota, Duluth, Minnesota
7.1. Introduction
7.1.1. SLC16 Gene Family: MCTs
7.1.2. SLC5 Gene Family: SMCTs
7.2. MCT and SMCT Transporter Expression
7.2.1. Tissue Distribution and Subcellular Localization of MCTs
7.2.2. Tissue Distribution and Subcellular Localization of SMCTs
7.3. Regulation of Gene Expression and Activity
7.3.1. Regulation of Gene Expression
7.3.2. Intracellular Trafficking
7.3.3. Regulation of Transporter Activity
7.4. Clinical Applications and Implications for Drug Delivery
7.4.1. Substrates
7.4.2. Inhibitors
7.4.3. Implications in Physiology and Disease Treatment
7.4.4. Drug Design
References
 
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