Graphics Reference
In-Depth Information
display, users can either use the scroll bars to visualize a certain region of the display
or to zoom out in order to visualize the overall structure with an averaging effect, as
used in a typical computer graph.
Average linkage clustering trees are then employed to sort the resulting
Jaccard
distance matrices for genes and pathways and the corresponding binary data matrix,
see Fig. . .he association structure between genes and among pathways can now
be comprehended using the three corresponding permuted matrix maps. In the up-
per let corner of the data matrix and the upper-let corners of the proximity maps
for genes and pathways we can identify several groups of genes that are involved in
the activities of only a few pathways, and several small groups of pathways that share
Figure . . Binary data matrix for the reduced Dataset ( genes (rows)for pathways(columns))
with two Jaccard proximity matrices for genes and for pathways sorted by average linkage trees in both
directions
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