Graphics Reference
In-Depth Information
Figure
.
.
[his figure also appears in the color insert.] Data matrix map (log
ratio gene
expression) with two proximity matrix maps (Pearson correlation for both genes and arrays) for
Dataset
permuted by two average linkage trees (for genes (rows) and arrays (columns))
. For the column (array) proximity matrix:
a) Search for coherent clusters of arrays along the main diagonal of the corre-
lation (maybe distance in other circumstances) matrix with dark red points.
Two dominant groups of arrays can be identified around the middle and the
lower-right corner of the correlation matrix, with several small but coher-
ent clusters scattered along the main diagonal. Let's denote these two major
groups of arrays as A
and A
. he arrays grouped into these clusters must
have similar expression patterns across all
genes (which will be exam-
ined in later steps).
