Some Major Steps in the Understanding of the Chemistry and Biochemistry of Chl - Chlorophyll Biosynthesis and Technological Applications - page 16

1.2.42 Smith and Rebeiz, 1977
In 1977, Smith and Rebeiz, described the enzymic insertion of Mg into Proto,
in higher plants in organello, to yield Mg-Proto (Smith and Rebeiz 1977 ).
The formation of Mg-Proto was accompanied by the formation of Zn-Proto.
1.2.43 Mattheis and Rebeiz, 1977a
In 1977, Mattheis and Rebeiz, described the conversion of exogenous Proto to
Pchlide a , in organello in higher plants (Mattheis and Rebeiz 1977a ).
1.2.44 Mattheis and Rebeiz, 1977b
In 1977, Mattheis and Rebeiz also, described the conversion of exogenous Mpe to
Pchlide a , in organello in higher plants (Mattheis and Rebeiz 1977b ).
1.2.45 Griffiths, 1978
In 1978, Griffiths, proposed that the Pchl holochrome i.e. Pchlide a oxidoreductase,
NADPH and Pchlide a form a photoactive ternary Pchlide a NADPH-enzyme
complex with a red absorption maximum at 652 nm (Griffiths 1978 ).
1.2.46 Belanger and Rebeiz, 1979
In 1979, Belanger and Rebeiz, reported that the Pchlide a pool of etiolated tissues
consisted of two components (probably MV and DV components) which are
photoconvertible into two distinct Chlide a species (Belanger and Rebeiz 1979 ).
This work heralded the discovery of the Chl biosynthetic heterogeneity and multi-
ple Chl biosynthetic routes.
1.2.47 Battersby and Jordan and Seerah, 1979
In 1979, Battersby et al., and Jordan and Seerah, determined that
1-hydroxymethylbilane (HMBL) (also called preuroporphyrinogen) is the immediate
precursor of Uroporphyrinogen III (Battersby et al. 1979 ;JordanandSeehra 1979 ).