Chemistry Reference
In-Depth Information
54. CogState Schizophrenia Battery, 195 Church St, New Haven, CT 06510,
USA.
55. B. N. Rogers, Emerging Frontiers in Basic Research and Clinical Sciences,
San Diego, 2007; Invited Lecture at Nicotinic Acetylcholine Receptors as
Therapeutic Targets.
56. D. A. Price, J. Blagg, L. Jones, N. Greene and T. Wager, Expert Opin. Drug
Metab. Toxicol., 2009, 5, 921.
57. P. R. McGuirk, M. R. Jefson, D. D. Mann, N. C. Elliott, P. Chang, E. P.
Cisek, C. P. Cornell, T. D. Gootz, S. L. Haskell, M. S. Hindahl, L. J.
LaFleur, M. J. Rosenfeld, T. R. Shryock, A. M. Silvia and F. H. Weber, J.
Med. Chem., 1992, 35, 611.
58. Concurrently a group at Sanofi Aventis also discovered this series, as
highlighted by SR-180711: (a) B. Biton, O. E. Bergis, F. Galli, A. Nedelec,
A. W. Lochead, S. Jegham, D. Godet, C. Lanneau, R. Santamaria,
F. Chesney, J. LeĀ“ onardon, P. Granger, M. W. Debono, G. A. Bohme,
F. Sgard, F. Besnard, D. Graham, A. Coste, A. Oblin, O. Curet, X. VigeĀ“ ,C.
Voltz, L. Rouquier, J. Souilhac, V. Santucci, C. Gueudet, D. Francon, R.
Steinberg, G. Griebel, F. Oury-Donat, P. George, P. Avenet and
B. Scatton, Neuropsychopharmacology, 2007, 32, 1; (b) P. Pichat, O. E.
Bergis, J.-P. Terranova, A. Urani, C. Duarte, V. Santucci, C. Gueudet,
C. Volts, R. Steinberg, J. Stemmelin, F. Oury-Donat, P. Avenet, G. Griebel
and B. Scatton, Neuropsychopharmacology, 2007, 32, 17; (c) S. Barak,
M. Arad, A. De Levie, M. D. Black, G. Griebel and I. Weiner, Neu-
ropsychopharmacology, 2009, 34,1.
59. C. J. O'Donnell, L. Peng, B. T. O'Neill, E. P. Arnold, R. J. Mather, S. B.
Sands, A. Shrikhande, L. A. Lebel, D. K. Spracklin and F. M. Nedza,
Bioorg. Med. Chem. Lett., 2009, 19, 4747.
60. C. J. O'Donnell, B. N. Rogers, B. S. Bronk, D. K. Bryce, J. W. Coe, K. K.
Cook, A. J. Duplantier, E. Evrard, M. Hajos, W. E. Hoffmann, R. S.
Hurst, N. Maklad, R. J. Mather, S. McLean, F. M. Nedza, B. T. O'Neill,
L. Peng, W. Qian, M. M. Rottas, S. B. Sands, A. W. Schmidt, A. V.
Shrikhande, D. K. Spracklin, D. F. Wong, A. Zhang and L. Zhang,
J. Med. Chem., 2010, 53, 1222.
61. See ref. 62 for details of the assays.
62. X. Hou, P. R. Verhoest, A. Villalobos and T. Wager, presented at the 238th
National Meeting of the American Chemical Society, Washington, 2009,
abstr. COMP-135.
63. B. Feng, J. B. Mills, R. E. Davidson, R. J. Mireles, J. S. Janiszewski,
M. D. Troutman and S. M. de Morais, Drug Metab. Dispos., 2008,
36, 268.
64. A. Ennaceur and J. Delacour, Behav. Brain Res., 1988, 31, 47.
65. M. W. Quick and R. A. Lester, J. Neurobiol., 2002, 53, 457.
66. Y. Sun, R. Olson, M. Horning, N. Armstrong, M. Mayer and E. Gouaux,
Nature, 2002, 417, 245.
67. S. Grimwood and P. R. Hartig, Pharmacol. Ther., 2009, 122, 281.
68. C. L. Shaffer, Annu. Rep. Med. Chem., 2010, 45, in press.
Search WWH ::




Custom Search