The Discovery of OSI-906, a Small-molecule Inhibitor of the Insulin-like Growth Factor-1 and Insulin Receptors - Accounts in Drug Discovery Case Studies in Medicinal Chemistry - page 91

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IGF-1R

IR

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Kinases

Figure 4.9 Selectivity profile of OSI-906 at a concentration of 1 mM when profiled using the ProfilerPro t Kinase Selectivity Assay Kit (Caliper

Life Sciences) against protein kinases representing the tyrosine and serine/threonine kinase families.