Biology Reference
In-Depth Information
innovations have recently been made within the fi eld to make target-
ing of RNA sequences a reality. This can be achieved in either a
specifi c or a nonspecifi c fashion, albeit distinct advantages and
disadvantages are associated with either approach. Moreover, the
selection of targeting agent (e.g., small molecule, peptide, oligo-
nucleotide) is also very diverse and should be fi ne-tuned for the
desired application. Overall, the modulation of miRNA maturation
is rapidly advancing, providing new insights and therapeutic agents
every year. This progress is poised only to accelerate as new tools
and understandings further demonstrate the importance of
miRNAs.
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