MicroRNA Maturation and Human Disease - miRNA Maturation: Methods and Protocols - page 24

and the RNA-induced silencing complex (RISC)
components Argonaute-1, Argonaute-2, PACT,
TARBP1, and TARBP2 in epithelial skin cancer.
Mol Carcinog. doi: 10.1002/mc.20861

66. Nana-Sinkam SP, Croce CM (2013) Clinical
applications for microRNAs in cancer. Clin
Pharmacol Ther 93(1):98-104. doi: 10.1038/
clpt.2012.192
67. Bonetta L (2009) RNA-based therapeutics:
ready for delivery? Cell 136(4):581-584.
doi: 10.1016/j.cell.2009.02.010
68. Highleyman L (1998) Fomivirsen. BETA 29: 31
69. Razonable RR (2011) Antiviral drugs for
viruses other than human immunodefi ciency
virus. Mayo Clin Proc 86(10):1009-1026.
doi: 10.4065/mcp.2011.0309
70. Davies BP, Arenz C (2006) A homogenous
assay for micro RNA maturation. Angew Chem
Int Ed Engl 45(33):5550-5552
71. Davies BP, Arenz C (2008) A fl uorescence
probe for assaying micro RNA maturation.
Bioorg Med Chem 16(1):49-55
72. Neubacher S, Dojahn CM, Arenz C (2011) A rapid
assay for miRNA maturation by using unmodifi ed
pre-miRNA. ChemBioChem 12(15):2302-2305.
doi: 10.1002/cbic.201100445

58. Pellegrino L, Jacob J, Roca-Alonso L, Krell J,
Castellano L, Frampton AE (2013) Altered
expression of the miRNA processing endoribo-
nuclease Dicer has prognostic signifi cance in
human cancers. Expert Rev Anticancer Ther
13(1):21-27. doi: 10.1586/era.12.150
59. Jafarnejad SM, Ardekani GS, Ghaffari M,
Martinka M, Li G (2012) Sox4-mediated Dicer
expression is critical for suppression of mela-
noma cell invasion. Oncogene. doi: 10.1038/
onc.2012.239
60. Shan G, Li Y, Zhang J, Li W, Szulwach KE,
Duan R, Faghihi MA, Khalil AM, Lu L, Paroo
Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He
C, Jin P (2008) A small molecule enhances
RNA interference and promotes microRNA
processing. Nat Biotechnol 26(8):933-940.
doi: 10.1038/nbt.1481
61. Newman MA, Hammond SM (2010)
Emerging paradigms of regulated microRNA
processing. Genes Dev 24(11):1086-1092.
doi: 10.1101/gad.1919710
62. Krutzfeldt J, Rajewsky N, Braich R, Rajeev KG,
Tuschl T, Manoharan M, Stoffel M (2005)
Silencing of microRNAs in vivo with
'antagomirs'. Nature 438(7068):685-689
63. Lindow M, Kauppinen S (2012) Discovering the
fi rst microRNA-targeted drug. J Cell Biol
199(3):407-412. doi: 10.1083/jcb.201208082

73. Bose D, Jayaraj G, Suryawanshi H, Agarwala P,
Pore SK, Banerjee R, Maiti S (2012) The
tuberculosis drug streptomycin as a potential
cancer therapeutic: inhibition of miR-21 func-
tion by directly targeting its precursor. Angew
Chem Int Ed Engl 51(4):1019-1023.
doi: 10.1002/anie.201106455
74. Connelly CM, Thomas M, Deiters A (2012)
High-throughput luciferase reporter assay for
small-molecule inhibitors of microRNA function.
J Biomol Screen. doi: 10.1177/108705711
2439606 64. Hu J, Xu Y, Hao J, Wang S, Li C, Meng S

(2012) MiR-122 in hepatic function and liver
diseases. Protein Cell 3(5):364-371.
doi: 10.1007/s13238-012-2036-3
65. Karakatsanis A, Papaconstantinou I, Gazouli M,
Lyberopoulou A, Polymeneas G, Voros D (2011)
Expression of microRNAs, miR-21, miR-31,
miR-122, miR-145, miR-146a, miR-200c, miR-
221, miR-222, and miR-223 in patients with
hepatocellular carcinoma or intrahepatic cholan-
giocarcinoma and its prognostic signifi cance. Mol
Carcinog. doi: 10.1002/mc.21864

75. Gumireddy K, Young DD, Xiong X, Hogenesch
JB, Huang Q, Deiters A (2008) Small-molecule
inhibitors of microrna miR-21 function. Angew
Chem Int Ed Engl 47(39):7482-7484.
doi: 10.1002/anie.200801555
76. Young DD, Connelly CM, Grohmann C, Deiters
A (2010) Small molecule modifi ers of
microRNA miR-122 function for the treatment
of hepatitis C virus infection and hepatocellular
carcinoma. J Am Chem Soc 132(23):7976-
7981. doi: 10.1021/ja910275u