Biomedical Engineering Reference
In-Depth Information
14
Effects of
fullerenes and
single-wall carbon
nanotubes on
murine and human
macrophages
Carbon
, 2006,
44
, 1100-1105
Puriied SWCNTs
1. Murine
macrophage
cells (J 774 cell
line)
2. Human
monocytes
derived
macrophages
Low cytotoxicity
Concentration
range:
30-60 μg/mL
15
Functionalization
density dependence
of single-walled
carbon nanotubes
cytotoxicity in vitro
Toxicology
Letters
,
2006,
161
(2),
135-142
Four water-dispersible
SWNT samples:
1. SWCNT-phenyl-SO
3
H
2. SWCNT-phenyl-
(COOH)
2
3. SWCNT in 1%
pluronic F108
4. SWCNT-phenyl-
SO
3
Na
Human dermal
ibroblasts (HDF)
Covalent functionalisation
reduced HDF cytotoxic
response
Overall, limited impact on
cell viability.
Concentration
range:
3-30 mg/mL
16
Cytotoxicity
assessment of some
carbon nanotubes
and related carbon
nanoparticle
aggregates and
the implications
for anthropogenic
carbon nanotube
aggregates in the
environment
International
Journal of
Environment
Research and
Public Health
,
2005,
2
(1),
31-42
Pristine SWNT sample
Two different
MWCNT
samples
from two
companies.
Murine alveolar
macrophages
(RAW267.9 cells)
Signiicant cytotoxic effect.
Induction of cellular death at
a threshold of 2.5 μg/mL
Concentration range
used:
10 μg/mL with
11 doubling
concentrations
subsequently
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