TOXICITY OF CARBON NANOTUBES - Carbon Nanotubes: From Bench Chemistry to Promising Biomedical Applications - page 225

10 The degree

and kind of
agglomeration
affect carbon
nanotube
cytotoxicity

Toxicology
Letters , 2007,
168 , 121-131

Four different fractions:
1. CNT-raw material
2. CNT-agglomerates
3. CNT-bundles
4. CNT-pellet

Mesothelioma cell
line (MSTO-211H)

All CNTs fractions were able
to signiicantly decrease cell
activity and proliferation in a
dose-dependent way

Concentration range
used: 7.5-30 g/mL

11 Investigation of the

cytotoxicity of CCVD
(catalytic chemical
vapour deposition)
carbon nanotubes
towards human
umbilical vein
endothelial cells

Carbon , 2006,
44 , 1093-1099

Three different
samples, each
synthesised by different
catalytic chemical
vapour deposition

Human umbilical
vein endothelial
cells (HUVEC)

Non-toxic Concentration

range: 100-1%
(vol/ vol)
Volume used: 100
μL

12 In-vitro studies of

carbon nanotubes
biocompatibility

Carbon , 2006,
44 , 1106-1111

High purity
MWNTs
coated on
polysulfone
ilms

1. Human
osteoblastic line
hFOB 1.19 ATCC
CRL-11372
2. Human
ibroblastic line
HS-5 ATCC CRL-
11882

Good biocompatibility Not applicable

13 Spectroscopic

analysis conirms
the interaction
between single
walled carbon
nanotubes and
various dyes
commonly used to
assess cytotoxicity

Carbon 2007,
45 , 1425-1432

Pristine SWCNTs Human alveolar

carcinoma
epithelial cell line
(A549)

Toxicity was observed Concentration range

used:
0.00156-0.8 mg/mL