Biomedical Engineering Reference
In-Depth Information
5
20
18
4
16
3
14
2
12
1
10
0
8
10
20 30
ARC-704 concentration (nM)
40
50
10
20
30
40
50
A
B
ARC-704 concentration (nM)
25
2.5
20
2
15
1.5
10
1
5
0.5
0
0
0
5 10
ARC-704 concentration (nM)
15
20
25
10
20
ARC-704 concentration (nM)
30
40
50
C
D
5
18
4
16
3
14
2
12
1
10
0
8
1
1.4
2
1.2
1.6
1.8
2.6
2.65
2.7
Fractal dimension,
D
f2
2.75
2.8
2.85
2.9
F
Figure 4.4
(a) Increase in the binding rate coefficient, k
1
with an increase in the ARC-704 concentration
(in nM) in solution. (b) Increase in the binding rate coefficient, k
2
, with an increase in the ARC-704
concentration (in nM) in solution. (c) Increase in the dissociation rate coefficient, k
d
, with an
increase in theARC-704 concentration (in nM) in solution. (d) Decrease in the binding rate
coefficient ratio, k
2
/k
1
with an increase in the ARC-704 concentration (in nM) in solution. (e)
Increase in the binding rate coefficient, k
1
with an increase in the fractal dimension, D
f1
. (f) Increase
in the binding rate coefficient, k
2
with an increase in the fractal dimension, D
f2
.
E
Fractal dimension,
D
f1
Continued
