Biomedical Engineering Reference
In-Depth Information
Table 4.1: Binding and dissociation rate coefficients for different concentrations (in nM) of C
in solution to ARC-704
immobilized on a surface plasmon resonance (SPR) biosensor surface ( Viht et al., 2007 ).
a
C a concentration,
nM
k
k 1
k 2
k d
k d1
k d2
50
10.777
1.680
6.540
0.876
2.165
0.256
3.993
0.239
na
na
25
5.091
0.699
2.831
0.173
11.53
0.050
1.721
0.172
na
na
10
1.1174
0.312
0.5869
0.1461 6.321
0.094
1.484
0.158
na
na
5
0.8764
0.165
0.5646
0.0956 3.344
0.087
0.926
0.0798
na
na
2.5
0.1726 0.026
0.1396 0.0130 2.136 0.0194
0.0579 0.0186
0.00921 0.00286
1.0175 0.0053
Table 4.2: Fractal dimensions for the binding and dissociation phase rate for different concentrations (in nM) of C
in solution to
a
ARC-704 immobilized on a surface plasmon resonance (SPR) biosensor surface ( Viht et al., 2007 ).
C
concentration,
nM
a
D f
D f1
D f2
D fd
D fd1
D fd2
50
2.5244
0.0951
1.9454
0.293
2.855
0.027
2.152
0.027
na
na
25
2.3454
0.0844
1.809
0.121
2.729
0.010
1.907
0.112
na
na
10
1.8220
0.162
1.279
0.287
2.631
0.057
2.040
0.119
na
na
5
1.914 0.113
1.545 0.202
2.536 0.0994
2.024 0.0977
na
na
2.5
1.504
0.0921
1.339
0.115
2.633
0.0349
0.0849
0.459
0.00921
0.00286
2.4906
0.0208
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