Biomedical Engineering Reference
In-Depth Information
4. Microfabricated electrochemical probe for
the detection of signaling proteins
released by single cells (
Corgler et al., 2010
)
5. Enhancing sensitivity of molecular biosensors through self-assembly (
Wei et al., 2010
)
6. Detection of amyloid precursor protein (APPTTO) using spectroscopic ellipsometry
and QCM techniques (
Mustafa et al., 2010
)
7. Biomolecule/metal nanoparticle composites on electrodes for sensing biofuel cells
and photoelectrochemical applications (
Tel-Vered et al., 2010
)
8. Single molecule applications for high-resolution AFM topography and recognition
imaging (
Ebner et al., 2010
)
9. Biomarker pattern analysis as an analytical system in the evaluation of an atheroscle-
rotic rich profile (
Siegel et al., 2010
)
10. Biosensors: a mixed market (
Neuman and Turner, 2010
)
A conference held in Baltimore, Maryland from May 5-7, 2010 on, “Sample preparation for
virus toxin, and pathogen detection and identification” (
Mello, 2010
) discussed different
sample preparation procedures to assist in the detection of harmful pathogens.
McLaughlin
(2010)
of the U.S. Army indicates that the detection and identification of biological warfare
agents rely heavily on the ability to purify, enrich, and concentrate molecular targets prior to
analysis. Note that the use of analytical technologies in the field is complicated or limited by
available methods for processing a wide variety of sample types into a form compatible with
multiple analytical technologies, such as biosensors.
Some of the presentations scheduled are on:
(a) Sample preparation and microfluidic technologies (
Maricella, 2010
)
(b) Point-of-test sample prep and molecular analysis (
Gau, 2010
)
(c) Sample preparation as a part of an integrated fluidic process for rapid diagnostics
(
Clarkson, 2010
)
(d) A fully integrated system for nucleic acid-based detection of bacteria and viruses in
biological samples at POC (point-of-care) (
Bau, 2010
)
(e) A novel preanalysis system for rapid, quantitative diagnostics (
Feaster, 2010
)
At the recent 2nd European Congress on Immunology in Berlin, Germany (from September
13-16, 2009) there were quite a few research papers including poster presentations that ana-
lyzed different biosensor applications for use in clinical laboratories, not the ones for general
home-use such as the glucose biosensor. Both researchers and vendors of different biosensor
applications confirmed the above view that the biosensors were being developed for clinical
laboratory usage only. Very little, if any, market research or survey has been done to help
develop these newer biosensors for home use. Of course, economic feasibility will still have
to be discussed with the administration to bring these biosensors into home use.
