Biomedical Engineering Reference
In-Depth Information
3.3 Conclusions
Different biosensor fabrication methods have been presented here. Some of the methods pres-
ented initially are dealt with in detail, whereas towards the end of the chapter others pres-
ented are only briefly alluded too. This is to prevent the biosensor fabrication chapter from
becoming unmanageable in size. The examples of biosensor fabrication presented are
selected at random from the literature. The only driving criterion, as is to be reasonably
expected, is that these examples have recently appeared in the literature. Though glucose bio-
sensor fabrication methods presented appear frequently, other examples of biosensor fabrica-
tion are also presented. Some of the biosensor fabrication presented include those for glucose
(biosensor using a nanocomposite electrode,
Safavi et al., 2009
; screen-printed water-based
carbon-ink microband biosensor,
Pemberton et al., 2009
; immobilized enzyme biosensor,
Lu et al., 2007
; ZnO nanoparticle/glucose oxidase biosensor,
Ren et al., 2009
; osmium com-
plex and glucose oxidase biosensor,
Salimi et al., 2009
; microencapsulated enzyme in a
hydrophobic synthetic latex film biosensor, Cosnier et al., 2000a,b; platinum nanowire array
biosensor,
Yang et al., 2006
). Other fabrication techniques for biosensor fabrication men-
tioned include MI (for a potentiometric protein biosensor,
Wang et al., 2008
; polymer micro-
array on a chip,
Henry et al., 2008
), inkjet printing technology for an optical fiber imaging
sensor (
Carter et al., 2006
), conducting polymer polyaniline (Pani)-based biosensors (using
ITO,
Tahir et al., 2007
; biosensor fabrication procedure based on processable polyaniline
nanoparticles,
Morrin et al., 2005a,b
; biosensor fabrication based on screen printing technol-
ogy (DNA chips with an electrical readout for the detection of viral DNA),
Schuller et al.,
2009
; microband glucose biosensor,
Pemberton et al., 2009
; disposable screen printed
electrodes (
Kadara et al., 2009
) biosensor based on charge transfer technique (
Lee et al.,
2009
), biosensor fabrication based on nanowire NEA (
Yang et al., 2006
), fabrication of
dip-strip test systems (
Bagal-kestwal et al., 2009)
, recrystallization technologies to fabricate
a Si nanowire biosensor
(Ashburn and Sun, 2009)
, and porous silicon-based biosensor
(
Matthew and Alocilja, 2003
).
The presentation of different biosensor fabrication techniques together in one chapter quickly
provides one with an overall perspective of the different fabrication techniques that have
appeared in the recent literature, of the techniques that exhibit potential, and techniques that
are being explored further research-wise. Needless to say, the fabrication techniques are
application dependent, such as the determination of glucose, but as one might very rea-
sonably expect, biosensors for the detection of other analytes is slowly but surely gaining
importance and thus biosensor fabrication techniques other than for glucose detection need
to be explored further. Surely, some of the biosensor fabrication techniques used for glucose
determination may also be used for the fabrication of biosensors (with suitable modifications,
if necessary) for the detection of other analytes of importance. It is very reasonable to expect
that if the biosensor for the detection of some particular analyte is to be developed, then
