Biomedical Engineering Reference
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Table 16.12: Binding rate coefficients and fractal dimensions for the hybridization of 50 mM cDNA in solution at pH 8.0
( Li et al., 2001 ).
Ion (MgCl 2 )
concentration
(mM)
k
k 1
k 2
D f
D f1
D f2
0.1
0.00043
0.00005 0.000226
0.000009
0.1813
0.00036 1.2886
0.1191
1.0842
0.0536 2.9105
0.00162
1
0.00234
0.00097 0.001195
0.00013
0.05231
0.00104 1.5648
0.1046
1.2708
0.1563 2.3546
0.07922
10
0.006961
0.000824
0.003359 0.000352 0.09877 0.0017 1.6138 0.06710 1.3672 0.1132 2.3378 0.04482
100
0.0802 0.01555 0.003981 0.000438
0.4834 0.0079 2.1698 0.1172
1.0788 0.2786 2.6728 0.02882
500
0.06276
0.01168 0.007705
0.000896
0.6786
0.0066 2.0704
0.1051
1.3266
0.1786 2.7308
0.02306
Effect of ion concentration.
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