Biomedical Engineering Reference
In-Depth Information
are of considerable value because they directly link the binding rate coefficient either to the
degree of heterogeneity that exists on the sensor surface or to the analyte concentration in solu-
tion. This provides a means by which the binding rate coefficient may be manipulated by either
changing the degree of heterogeneity on the sensor chip surface or by changing the analyte con-
centration in solution as the case may be. The really interesting test of the fractal model would
be its ability to make a prediction that turns out to be correct. This would prove to be extremely
valuable, especially in the detection of protein biomarker(s) and medically-related analytes.
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