Biomedical Engineering Reference
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26000
45000
24000
40000
22000
35000
20000
30000
18000
16000
25000
14000
20000
12000
15000
10000
8000
100
10000
200 300 400
Template concentration (nM)
500
100
200 300
Template concentration (nM)
400
500
B
A
26000
40000
24000
35000
22000
20000
30000
18000
25000
16000
14000
20000
12000
15000
10000
10000
8000
2.52
2.54
2.56 2.58
Fractal dimension, D f1
2.6
2.62
2.64
2.8
2.85 2.9 2.95
Fractal dimension, D f2
2.3
C
D
1.7
1.65
1.6
1.55
1.5
1.45
1.4
1.11
1.115
1.12
1.125
D f2 / D f1
1.13
1.135
1.14
E
Figure 11.18
(a) Increase in the binding rate coefficient (a) k 1 and (b) k 2 with an increase in the template
concentration (in nM) (c) Decrease in the binding rate coefficient, k 1 , with an increase in the fractal
dimension, D f1 (d) Decrease in the binding rate coefficient, k 2 , with an increase in the fractal
dimension, D f2 (e) Increase in the ratio of the binding rate coefficients, k 2 /k 1 , an increase in the
ratio of the fractal dimensions, D f2 /D f1.
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