Detection of Analytes on Arrays/Microarrays/DNA Chips - Biosensors and Biosensor Kinetics - page 311

Table 11.5: Fractal dimensions for the binding and the dissociation phases for the hybridization of different analytes in solution to
complementary or noncomplementary receptors immobilized on different biosensor surfaces.

Analyte in Solution/
Receptor on Surface Biosensor Type D f D f1 D f2 D f3 D fd References

QCM 3,3-diaminobenzidine/

sterptavidin-peroxide
horseradish (SA-HRP)

1.4132 0.3062 0.7886 0.2512 2.7684 0.01818 na na Feng et al.

(2007

Electrochemical
enzymatic
genosensor

Sequence of the SARS
(severe acute respiratory
syndrome) coronavirus
(CoV) SARS-CoV/(c-
DNA) 30-mer 3 0 -
thiolated DNA strand

1.9290 0.2812 na na na na Abad-Valle

et al.
(2007a,b )

Electrochemical
enzymatic
genosensor

Sequence of the SARS
(severe acute respiratory
syndrome) coronavirus
(CoV) SARS-CoV/3 base
mismatch 30-mer 3 0 -
thiolated DNA strand

2.7530 0.2030 na na na na Abad-Valle

et al.
(2007a,b )

Electrochemical
detection

p-aminophenylbutyrate/
esterase 2 from
Alicyclobacillus
acidocaldarius plus
oligodeoxynucleotide
(ODN) in a site-specific
manner (perfectly
matched; ODN-P)

1.4252 0.2030 0.4432 0.2182 2.5556 0.1208 na 0.5014

0.1011

Wang et al.
(2007 )

Electrochemical
detection

p-aminophenylbutyrate/
esterase 2 from
Alicyclobacillus
acidocaldarius plus
oligodeoxynucleotide
(ODN) in a site-specific
manner
(noncomplementary
ODN; ODN-N)

0.5602 0.2460 0. þ 0.4148 1.78902 0.2730 2.4304 na Wang et al.

(2007 )

0.1647