Biomedical Engineering Reference
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Table 9.9 Binding and dissociation rate coefficients for TN-XL and two other GECI (YC2.0 and GCaMP1.6) response kinetics
using identical stimulus conditions (AP-frequency 40 Hz, 2.2 s) ( Mank et al., 2006 ).
Analyte
k
k 1
k 2
k d
k d1
k d2
TN-XL
1.1497 0.0044
na
na
0.2413 0.5659
0.03368 0.5639 0.3943 0.0360
YC 2.0
0.6703
0.0829
na
na
0.2965
0.1259
0.3682
0.1259 0.5697
0.0770
GCAMP13
0.7729
0.1234
na
na
0.3790
0.2237
0.4984
0.0537 0.9046
0.0092
Table 9.10 Fractal dimensions for the binding and the dissociation phase for TN-XL and two other GECI (YC2.0 and GCaMP1.6)
response kinetics using identical stimulus conditions (AP-frequency 40 Hz, 2.2 s) ( Mank et al., 2006 ).
Analyte
D f
D f1
D f2
D fd
D fd1
D fd2
TN-XL
1.6630
0.0044
na
na
0
þ
1.4778
0
þ
0.4146
0.
þ
0.3994
YC 2.0
1.1896
0.3912
na
na
1.1322
0.2666
0.254
þ
0.2578
2.3436
0.04462
GCAMP13
0.9670 0.1999
na
na
0 þ 0.731
0 þ 0.3030
2.7930 0.05614
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