Biomedical Engineering Reference
In-Depth Information
8
14
12
6
10
8
4
6
4
2
2
0
0
5
10
15
Time (min)
20
25
30
0
0
2
4
6
8
10
12
14
B
A
Time (min)
12
22
10
20
8
18
6
16
4
14
12
2
10
0
0
2
4
6
8
10
12
14
0
5
10
15
20
25
C
D
Time (min)
Time (min)
26
7
24
6
22
5
20
4
18
16
3
14
2
12
1
10
8
0
0
5
10
15
20
25
30
0 2 4 6 8 0 2 4 6
E
F
Figure 9.5
(a) Binding and dissociation of 20 nM m
Time (min)
Time (min)
CD-chol cells exposed to two cycles of cholesterol
enrichment (
Ziblat et al., 2006
). (b) Binding and dissociation of 20 nM m
b
CD-chol cells exposed
to two cycles of cholesterol enrichment (second cycle) (
Ziblat et al., 2006
). (c) Dissociation of
10 nM m
b
CD-chol cells (
Ziblat et al., 2006
). (d) Dissociation of 10 nM m
CD-chol cells followed
b
b
by inactive analog of m
CD (3 nM). (e) Binding of 10 mM m
CD-chol m
CD,
CD (3 nM).
b
b
b
a
(f) Dissociation of 3 nM inactive analog of m
CD. When only a solid line (--) is used then a
single-fractal analysis applies. When both a dashed (- - -) and a solid (--) line are used then the
dashed line represents a single-fractal analysis and the solid line represents a dual-fractal analysis.
CD,
b
a
