Physiological Cellular Reactions Detection on Biosensor Surfaces: A Fractal Analysis - Biosensors and Biosensor Kinetics - page 233

Table 9.3: Binding and dissociation rate coefficients for DMR signals mediated by different bradykinin concentrations ( Fang et al.,
2006 ) .

Analyte in
Solution/
Receptor on
Surface (nM) k k 1 k 2 k d k d1 k d2

10 6 128 0.01181 0.001816 1.0036 0.00007

0.000051

5.6 0.2519

2.810 6 0.0038 0.000181 0.0207 0.0093

6.910 5 64 0.03889

0.00559

0.1757
0.00227

0.3078
0.0089

0.000541
0.000322

0.2285
0.0054

2.610 5

5.210 5 32 0.001796

0.000379

0.000643
0.000057

0.06998
0.00418

0.000216
0.000071

0.04512
0.00233

0.810 5

10 5 16 0.00209

0.000295

0.00148 0.03584 0.000233 9.8 0.00744

0.000542

10 5 0.00021 0.00219 0.00048 0.7

Table 9.4: Fractal dimensions for the binding and the dissociation phase for DMR signals mediated by different bradykinin
concentrations ( Fang et al., 2006 ) .

Analyte in
Solution/Receptor
on Surface (nM) D f D f1 D f2 D fd D fd1 D fd2

128 0.8092 0.2878 0 þ 0.1824 2.4906 0.1378 0 þ 0.3544 0 þ 0.4236 2.1566 0.1364

64 1.3818 0.1208 0.992 0.2338 2.1368 0.1216 0.2066 þ 0.3336 0 þ 0.3544 2.1960 0.0618

32 0.4442 0.1542 0 þ 0.1614 1.7420 0.1841 0.0432 þ 0.136 0 þ 0.14486 1.7582 0.1631

16 0.0696 0.0973 0.5376 0.1982 1.6696 0.2318 0.2410 0.1051 0 þ 0.07376 1.3452 0.2144