Biomedical Engineering Reference
In-Depth Information
FIGURE 1.11
Lateral force microscopy (LFM) images of nanolithography patterns, which were formed using an
eight-pen nanoplotter capable of doing parallel DPN
8
.
The applications of nanoscale manufacturing have also been used in the field of dental implan-
tology. Chapters 5-8 discuss briefly about nanotechnology applications in dental implantology,
microscale to nanoscale surface modification techniques, titanium nanotubes as carriers of osteo-
genic growth factors and antibacterial drugs and cellular responses to surface modifications, and their
applications in implantology and bone tissue engineering. Chapter 9 discusses about improving bio-
compatibility and bioactivity of titanium alloy (Ti6Al4V) by electrodeposition of TiO
2
nanoparticles.
Multiwalled carbon nanotubes/hydroxyapatite nanoparticles incorporated membranes have been
explored for their applications in guided tissue regeneration (GTR) of the periodontium (Chapter 10).
Poly(ethylene glycol) (PEG) hydrogel is fast emerging as a biocompatible material in implant den-
tistry. PEG hydrogel has been evaluated as a carrier scaffold for osteogenic growth factors and as a
guided bone regeneration (GBR) membrane. Microfabrication technique (soft photolithography) to
fabricate PEG hydrogel micropatterns and recent advances in use of PEG hydrogel as GBR mem-
brane has been covered in Chapter 11. Nano-apatitic composite scaffolds for stem cell delivery and
bone tissue engineering have been discussed in Chapter 12. The phenomenon of self-assembly of
proteins and peptides and their applications in bionanotechnology and dentistry are explained briefly
in Chapter 13. This is followed by a general discussion on bone regeneration using self-assembled
nanoparticle-based scaffolds in Chapter 14. In Chapter 15, the application of CVD technologies to
dental burs and tools has been presented. Nanomechanical characterization of mineralized tissues in
the oral cavity and nanoindentation techniques for the determination of mechanical properties of den-
tal materials and dental implants have been discussed in the subsequent Chapters 16-18.
8
Dr T. Okpalugo, University of Paisley (2007) Private communication.
