Biomedical Engineering Reference
In-Depth Information
(A)
1
µ
m
P
/
L
= 3.5
P
/
L
= 3. 0
P
/
L
= 2.5
(B)
700
600
500
400
300
200
100
0
0
2.5
5.0
Collagen mass fraction in CPC (%)
500
(C)
400
300
200
100
0
FIGURE 12.3
Nano-apatitic collagen-CPC composite. (A) SEM showing
collagen fibers (short arrows) covered with nano-apatite crystals
(long arrow). The nano-apatite had intimate contact with
collagen fibers. (B) Work-of-fracture, or toughness (mean
SD;
n
6) of CPC was increased with collagen content. P/L is the
CPC powder to liquid ratio. (C) MC3T3-E1 pre-osteoblastic cell
attachment
number of live cells/area of CPC (mean
SD;
