Biomedical Engineering Reference
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the characterization, we introduce some notation: Let F
03
(t) = 1 F
+
(t),
a
k
= (F
0k
(t
0
))
1
for k = 1; 2; 3, and for a nite collection of functions
g
1
;g
2
;:::, let g
+
denote their sum. Groeneboom et al. (2008b) show that
there exist almost surely a unique pair of convex functions ( H
1
; H
2
) with
right continuous derivatives ( S
1
; S
2
) satisfying
a
i
H
i
(h) + a
3
H
+
(h) a
i
V
i
(h) + a
3
V
+
(h) ; i = 1; 2 and h 2R;
(1)
Z
fa
i
H
i
(h)+a
3
H
+
(h)a
i
V
i
(h)a
3
V
+
(h)gd F
i
(h) = 0 i = 1; 2 ;
(2)
and
(3) For each M > 0 and i = 1; 2, there are points
1i
< M and
2i
> M
such that a
i
H
i
(h) + a
3
H
+
(h) = a
i
V
i
(h) + a
3
V
+
(h) for h =
i1
;
i2
.
The self-inducedness is clear from the above description as the defining proper-
ties of H
1
and H
2
must be written in terms of their sum. The random functions
S
i
are the limits of the normalized sub-distribution functions as Theorem 1.8
of Groeneboom et al. (2008b) shows:
fn
1=3
( F
i
(t
0
+ hn
1=3
) F
0i
(t
0
))g
i=1
!
d
(S
1
(h);S
2
(h))
in the Skorohod topology on D(R)
2
. Here, D(R) is the space of real-valued
cadlag functions onRequipped with the topology of convergence in the Sko-
rohod metric on compact sets. In particular, this yields convergence of finite-
dimensional distributions; thus, n
1=3
( F
i
(t
0
)F
0i
(t
0
)) !
d
S
i
(0) for each i. The
proof of the above process convergence requires the local rate of convergence
of the MLEs of F
01
and F
02
discussed earlier.
It is somewhat easier to characterize the asymptotics of the naive estima-
tor. Let H
i
denote the GCM of Vi
i
and let S˜i
i
denote the right derivative of
H
i
. Then,
fn
1=3
( F
i
(t
0
+ hn
1=3
) F
0i
(t
0
))g
i=1
!
d
( S
1
(h); S
2
(h)) :
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