Biomedical Engineering Reference
In-Depth Information
(Turnbull (1976)). Although several procedures have been developed for the
one-sample estimation problem, there does not exist much literature on the
topic. The same is true for the investigation of the use of parametric models
and inference procedures for the analysis of interval-censored data. One ma-
jor reason for this is that in most situations, there does not exist much prior
information about the variable under study, and thus one may prefer nonpara-
metric or semiparametric approaches rather than parametric approaches.
The implementation of the available inference procedures is clearly im-
portant and, for this, an essential part is the availability of some software
packages. Although there exist some functions or a toolbox in R and SAS,
there is no commercially available statistical software yet that provides an
extensive coverage for interval-censored data. This is perhaps due to the com-
plexity of both the algorithms and the theory behind it. Chapters 13 and 14
discuss two R packages for nonparametric comparison of survival functions
based on interval-censored data.
Bibliography
Anderson, P. K., Borgan, O., Gill, R. D., and Keiding, N. (1995). Statistical
Models Based on Counting Processes. New York: Springer.
Barrett, J. K., Siannis, F., and Farewell, V. T. (2011). A semi-competing
risks model for data with interval-censoring and informative observation:
An application to the mrc cognitive function and ageing study. Statistics
in Medicine 30, 1{10.
Betensky, R. A. (2000). On nonidentifiability and noninformative censoring
for current status data. Biometrika 87, 218{221.
Chen, B., Yi, G. Y., and Cook, R. J. (2010).
Analysis of interval-censored
 
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