Biomedical Engineering Reference
In-Depth Information
2.5x10
−
09
(A)
2.0x10
−
09
1.5x10
−
09
1.0x10
−
09
5.0x10
−
10
0
Healthy volunteers
Cardiac patients
2E
−
08
(B)
y = 0.0324x
−
2E
−
10
1.5E
−
08
1E
−
08
5E
−
09
0
Serum CRP (g/mL)
FIGURE 22.2
(A) Human salivary CRP levels in healthy volunteers (n
5
55) and in cardiac patients (n
5
28). (B) Correlation
of salivary CRP levels to plasma CRP levels
[9]
.
Early diagnosis of HNSCC holds the promise of improved prognosis but is currently impeded in
many patients who delay seeking medical attention due to a number of factors associated with
tobacco and alcohol intake. Moreover, if the tumors are tiny (unable to detect by modern cameras)
and/or located in areas in the oral cavity that are not easily accessible, saliva offers the opportunity
as a diagnostic medium for early detection since these tiny tumors secrete biomarkers that are
indicative of a pathological condition. More so, the direct impact of smoking can clearly be seen in
