Biomedical Engineering Reference
In-Depth Information
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
(I)
(J)
FIGURE 19.4
Clinical study with nano-HA (Ostim
s
) used for advanced intrabony defects. (A) Mesial aspect of tooth 34
prior to surgery with OFD
nano-HA depicting a probing depth of 10 mm. (B) Preoperative radiograph
demonstrating the presence of a deep intrabony defect. (C) Following removal of granulation tissue and
thorough scaling and root planing, the intraoperative situation revealed a deep one- and two-wall intrabony
defect. (D) The intrabony component was filled with nano-HA. (E) At 7 months following surgery, a substantial
reduction of probing depth was measured. (F) At 7 months, the intraoral radiograph revealed a hard tissue fill
of the intrabony component. (G) Removed biopsy. (H) Complete flap closure, immediately after biopsy
removal. (I) The histological evaluation revealed a healing predominantly characterized by a long junctional
epithelium and limited regeneration of cementum and bone. Red arrowhead: coronal extension of NC,
1
