Biomedical Engineering Reference
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With a similar method, bioglass@CNF hybrids can also be prepared by adding a ratio of tetraethyl
orthosilicate into CaP precursor solution. By varying their molar ratios, different bioglass-like 45S, 58S,
68S, etc. can be incorporated. Also, ion-doped CaP compounds embedded CNFs can be fabricated.
Considering the important role of Mg 2 1 and Zn 2 1 in bone growth [107] , we have also incorporated dif-
ferent amounts of Mg 2 1 and Zn 2 1 into
-TCP to achieve better osteoinductivity ( Figure 18.14 ). All
these alterations have provided a powerful way to produce CNFs with significantly improved biological
properties.
β
(A)
(B)
10
20
30
40
50
60
70
0
10
0 0 0 0 0
2-Theta (°)
70
2-Theta (°)
FIGURE 18.13
XRD patterns of (A) CNFs and (B)
β
-TCP@CNFs carbonized at 1373 K in N 2 for 2 h.
Reproduced with permission from Ref. [99] .
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
FIGURE 18.14
Element mapping analysis of ion-doped
β
-TCP@CNFs: (A
D) Ca 2.97 Mg 0.03 (PO 4 ) 2 @CNFs and (E
H)
Ca 2.99 Zn 0.01 (PO 4 ) 2 @CNFs.
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