Biomedical Engineering Reference
In-Depth Information
With a similar method, bioglass@CNF hybrids can also be prepared by adding a ratio of tetraethyl
orthosilicate into CaP precursor solution. By varying their molar ratios, different bioglass-like 45S, 58S,
68S, etc. can be incorporated. Also, ion-doped CaP compounds embedded CNFs can be fabricated.
Considering the important role of Mg
2
1
and Zn
2
1
in bone growth
[107]
, we have also incorporated dif-
ferent amounts of Mg
2
1
and Zn
2
1
into
-TCP to achieve better osteoinductivity (
Figure 18.14
). All
these alterations have provided a powerful way to produce CNFs with significantly improved biological
properties.
β
(A)
(B)
10
20
30
40
50
60
70
0
10
0 0 0 0 0
2-Theta (°)
70
2-Theta (°)
FIGURE 18.13
XRD patterns of (A) CNFs and (B)
β
-TCP@CNFs carbonized at 1373 K in N
2
for 2 h.
Reproduced with permission from Ref.
[99]
.
(A)
(B)
(C)
(D)
(E)
(F)
(G)
(H)
FIGURE 18.14
Element mapping analysis of ion-doped
β
-TCP@CNFs: (A
D) Ca
2.97
Mg
0.03
(PO
4
)
2
@CNFs and (E
H)
Ca
2.99
Zn
0.01
(PO
4
)
2
@CNFs.