Biomedical Engineering Reference
In-Depth Information
(A)
(B)
FIGURE 14.7
SEM image of 2.0% Ag
-tissue conditioner (A) as compared to control and (B) similar surface texture with
large porosity is seen (
250).
3
6 h with replacement of new distilled water from 24 to 72 h of storage. The quantity (mg/L) of Ag
1
was expressed as the amounts of Ag
1
in the solution per unit of surface area of the disc (cm
2
). The
quantities of released Ag
1
were dose dependent and decreased in all tested specimens as time elapsed
(
Figure 14.6
). The amount of eluted Ag
1
followed a steady state of approximately 0.08 mg/L in
0.5% of Ag
and 0.21 mg/L in 1.0% of Ag
after 48-h storage. In 2.0% Ag
-tissue conditioner, eluted
Ag
1
was detected as approximately 0.49 mg/L at 72 h with a steeper decrease as compared to others.
Considering in vivo tissue conditioners closely fitting the oral mucosa, further investigation would be
needed to clarify the main action of Ag
-embedded gel polymer whether the antimicrobial effects
resulted from Ag
1
elution or due to direct contact
[42
44]
or mixed effects.
14.4.2
Microstructure of Ag
-tissue conditioner composites
The microstructure of obtained Ag
-tissue conditioner was studied by scanning electron microscope
(SEM) equipped with energy dispersion spectroscopy. The Ag
loaded tissue conditioner was gold
