Biomedical Engineering Reference
In-Depth Information
CHAPTER
9
Silver and Phosphate Nanoparticles:
Antimicrobial Approach and Caries
Prevention Application
D.B. Barbosa
a
, D.R. Monteiro
a
, A.S. Takamyia
a
, E.R. Camargo
b
,
A.M. Agostinho
c
, A.C.B. Delbem
a
and J.P. Pessan
a
a
Sa˜o Paulo State University, Ara¸atuba Dental School, Brazil
b
LIEC-Department of Chemistry, Federal University of Sa˜o Carlos, Brazil
c
Center for Engineering Biofilm, Montanta State University, USA
CHAPTER OUTLINE
9.1 Welcome to nanoworld................................................................................................................. 187
9.2 Nanoparticles X “BUGS” ............................................................................................................... 190
9.2.1 Microbial biofilms and tolerance ................................................................................ 190
9.2.2 Silver nanoparticles and biofilms ............................................................................... 192
9.2.2.1 Mechanisms of action and literature data ......................................................... 192
9.2.2.2 Processing silver nanoparticles ....................................................................... 193
9.3 Phosphates micro- and nanoparticles and caries prevention........................................................... 195
9.3.1 De- and remineralization process ............................................................................... 195
9.3.2 Nanophosphates and microbial adhesion .................................................................... 195
9.4 Pros and cons of nanoparticles toward biological-dental application .............................................. 196
9.4.1 Toxicity.................................................................................................................... 196
9.4.2 Processing costs....................................................................................................... 197
9.4.3 Potential use in dental field and future directions ....................................................... 198
9.5 Conclusions................................................................................................................................. 198
References ......................................................................................................................................... 199
9.1
Welcome to nanoworld
For centuries, chemists have been able to organize matter, atom by atom, to make molecules.
Particularly, since the nineteenth century, organic chemistry has shown that nearly infinite number
of different molecules could be synthesized, isolated, and purified. Therefore, what is new in this
branch of science of the twenty-first century named nanoscience? Or, what
is the difference
