Biomedical Engineering Reference
In-Depth Information
CHAPTER
6
Nanostructured Dental Composites
and Adhesives with Antibacterial and
Remineralizing Capabilities for Caries
Inhibition
Hockin H.K. Xu
a
, Lei Cheng
b
, Ke Zhang
c
, Mary Anne S. Melo
d
, Michael D. Weir
a
, Joseph M.
Antonucci
e
, Nancy J. Lin
e
, Sheng Lin-Gibson
e
, Laurence C. Chow
f
and Xuedong Zhou
b
a
Department of Endodontics, Prosthodontics and Operative Dentistry, University of Maryland Dental School,
Baltimore, MD, USA,
b
State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, China,
c
Department of Orthodontics, School of Stomatology, Capital Medical University, Beijing, China,
d
Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceara, Fortaleza, CE, Brazil,
e
Polymers Division, National Institute of Standards and Technology, Gaithersburg, MD, USA,
f
Paffenbarger Research Center, American Dental Association Foundation, Gaithersburg, MD, USA.
CHAPTER OUTLINE
6.1 Introduction .................................................................................................................................
109
6.2 Development of antibacterial nanocomposite with CaP nanoparticles ..............................................
111
6.3 Durability of antibacterial nanocomposite in water-aging ...............................................................
114
6.4 Antibacterial dentin primer ...........................................................................................................
118
6.5 Antibacterial adhesive..................................................................................................................
120
6.6 Antibacterial and remineralizing adhesive containing NACP ...........................................................
123
6.7 Summary and conclusions ............................................................................................................
125
Acknowledgments ...............................................................................................................................
126
Disclaimer ..........................................................................................................................................
126
References .........................................................................................................................................
126
6.1
Introduction
Dental composites are increasingly popular due to their esthetics and direct-filling capabilities
[1,2]
. Extensive studies have been performed to improve the fillers, resins, and polymeriza-
tion properties
[3
11]
. Nonetheless, composites accumulated more biofilms/plaques than
