Biomedical Engineering Reference
In-Depth Information
the nanospots and the interaction with different concentrations of
their corresponding antigens was analyzed through the changes
in the extinction spectra (see Fig. 4.11). The detection limit of this
biosensor was 100 pg/mL.
Figure 4.11 Absorbance measurements at each spot using the multiarray
LSPR-based nanochip. After the introduction of antigens
at different concentrations using the nanoliter dispensing
system, the LSPR spectra were recorded for C-reactive protein
(CRP). Reprinted with permission from ref. 69, Copyright
2006, American Chemical Society. See also Color Insert.
Gold nanorods posses two plasmon bands: one is transverse
plasmon wavelength (TPW) and another is longitudinal plasmon
wavelength (LPW) appearing in visible or near-infrared range.
Because the LPW of gold nanorods can be ine-tuned by the length-
to-diameter aspect ratio of the nanorods, a signiicant multi-
 
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