Bioconjugation of Noble Metal Nanoparticles and Their Applications to Biolabeling and Bioimaging - From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection - page 25

them through images. Bioconjugation of noble metal nanoparticles
also determines their biomedical application depending on what
biomolecules are conjugated on the particle surface and which
functions are provided, e.g., DNA for DNA detection assays and
biolabeling markers, antibodies for speciic and selective targeting.
Each imaging modality has its own merits and demerits, but by
combining different modalities into an all-in-one single system,
multimodal imaging nanoagents may provide complementary
information for biologically motivated studies. All these imaging
methods using noble nanoagents present multiple imaging and are
promising to achieve single-molecule or multifunctional detections,
either in vivo or in vitro , for early diagnostics.
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