Mass Spectrometric Bioanalysis Assisted by Noble Metal Nanoparticles - From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection - page 274

Table 12.1 NPs used in LDI-MS without enrichment of analyte

Capping agent a Analyte b

Nps Size (nm) LOD Ref.

Au Citrate 2, 5, 10 Substance P 100 fmol 21

Au Citrate 13 Neutral steroid 188−641 nM 22

Au Citrate 13 Carbohydrate 1.3−0.7 μM 22

Au Citrate 13 Angiotensin I 5.1 μM 22

Au Citrate 13 Indoleamine 46 nM 22

Au Citrate 20−30 Angiotensin I <0.7 fmol 23

Au Citrate 20−30 Cytochrome c <5 pmol 23

Au Citrate 20−30 Insulin <5 pmol 23

<10 −7 mg/mL 23 Au Citrate 20−30 DDAC

<10 −5 mg/mL 23 Au Citrate 20−30 Pyrene

Au 4-ATP 5 Cytochrome c NG 24

Au 4-MBA 10 Angiotensin I NG 25

Au CHCA 20 Protein digest NG 26

Au No 12 Carbohydrate 82−151 nM 27

Au No 12 α-, β-, and γ-CD 0.25−0.5 μM 28

Au No 12 Insulin <100 μM 28

Au Substrate 10 Glycosyl

transferase

NG 29

Au No Nanorod Bradykinin <650 fmol 30

Au No Nanorod Insulin <2 pmol 30

Au Citrate 14 Aminothiol 1.0−1.3 μM 32

Au Aptamer 13 ATP 2.1 μM 33

Ag Citrate 160 Bradykinin <0.1 mg/mL 41

Ag Citrate 160 Angiotensin I <0.5 mg/mL 41

Ag NG 20, 60 Olein <274 pmol 42

Ag No 10, 20 Aminothiol 7-22 nM 43

Ag Octadecanethiol <50 Gramicidin in

urine

0.13 μM 46

Ag Octadecanethiol <50 Ubiquitin <25 nM 46

Ag Octadecanethiol <50 BSA <1 μM 46

Ag Citrate 34 Estrogens NG 48