Photoluminescence of Gold Nanoparticles and Their Applications to Sensing and Cell Imaging - From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection - page 181

Chapter 9
Photoluminescence of Gold
Nanoparticles and Their Applications
to Sensing and Cell Imaging
Chih-Ching Huang * and Yu-Shen Lin
Institute of Bioscience and Biotechnology and Center of Excellence for
Marine Bioenvironment and Biotechnology, National Taiwan Ocean University,
2, Beining Road, Keelung, 20224, Taiwan
* [e-mail]
Metallic nanomaterials, which are among the most fascinating
materials in modern science, exhibit unique optical, electronic,
magnetic, and catalytic properties. Because of their photo-optical
distinctiveness and biocompatibility, luminescent gold (Au)
nanomaterials have become interesting components in bioassays.
This chapter focuses on the preparation and bioapplications of
polymer-stabilized Au nanoclusters (NCs), thiol-stabilized Au NCs,
and luminescent Au nanoparticles (Au NPs, <2 nm). Varying the
experimental conditions, such as the molar ratio of the capping agent
to Au ions, allows the luminescence wavelengths of these systems to
be tuned from the ultraviolet to the near-infrared. The luminescence
quantum yields of Au NCs are several orders of magnitude higher
than those of bulk Au and larger Au NPs. The biocompatibility of
Au NCs and luminescent Au NPs has led to their application in the
detection of antibodies, proteins, and metal ions, as well as in cell
imaging.
From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetecon
Edited by Lai-Kwan Chau and Huan-Tsung Chang
Copyright © 2013 Pan Stanford Publishing Pte. Ltd.
ISBN 978-981-4267-24-3 (Hardcover), 978-981-4303-10-1 (eBook)
www.panstanford.com