Fabrication of Biosensor Chips - From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection - page 131

single window

single-phase e multi-window

multi-phase m multi-window

Figure 6.19 Schematic diagram of a variety of possible optical iber
windows.

6.5 Conclusions and Outlook

This chapter introduces four key technologies that are commonly
used to fabricate biosensor chips: photolithography, soft lithography,
fabrication of diffraction gratings, and production of optical iber
windows. Photolithography deines the microstructures in the
biosensor chips through optical exposure technique. Soft lithography
uses electrochemical processing technique to form metal molds in
order to deine the microstructures in biosensor chips. Grating or
optical iber window is often used in optical sensors. This chapter
has overviewed the techniques to construct gratings and optical iber
windows. Since optical iber after partial removal of cladding tends
to be fragile and easily lose optical signals during transmission, this
chapter has discussed how to re-process optical iber to produce
optical iber windows, so the iber not only transmits signals, and
is not as fragile, but also functions as a sensor and as a component
of the biosensor chip. Through the combined use of these four
technologies, biosensor chips can be manufactured using polymer
materials.

References

1. G. Shugar, and J. Ballinger, Chemical Technicians' Ready Reference
Handbook , (McGraw-Hill: New York, 1996).