Biomedical Engineering Reference
In-Depth Information
11.3 Conclusion
Nano-.and.low-micron-sized.particles,.whether.polymeric.or.lipid.based,.are.very.versa-
tile.tools.for.drug.delivery.applications..They.can.be.made.in.various.sizes,.from.various.
materials,.can.carry.molecules.of.different.chemistries,.and.can.be.modiied.for.targeting.
purposes..As.such,.they.are.indispensable.as.drug.carriers..And.with.the.advent.of.nano-
technology,. which. provides. tools. such. as. quantum. dots,. nanowires,. and. nanorods,. the.
ield.has.become.more.exciting.than.ever.
Acknowledgments
We. gratefully. acknowledge. the. support. by. METU. (BAP. 07.02.2009.00.01). through. which.
part.of.this study.was.conducted.
References
1 . Jain,.K.K.,  Drug delivery systems methods in molecular biology ,.Vol..437,.Humana.Press,.New.York,.
2008,. c hap..1.
. 2.. Uekama,. K.,. Hirayama,. F.,. and. Irie,. T.,. Cyclodextrin. drug. carrier. systems,. Chem. Rev. ,. 98,.
2045,.1998.
. 3.. Pankhurst,.Q.A.,.et.al.,.Applications.of.magnetic.nanoparticles.in.biomedicine,. J. Phys. D Appl.
Phys. ,.36,.R167,.2003.
. 4.. Torchillin,.V.,. Multifunctional pharmaceutical nanocarriers ,.Vol..4,.Springer,.New.York,.2008.
. 5.. Carmeliet,.P.,.and.Jain,.R.K.,.Angiogenesis.in.cancer.and.other.diseases,. Nature ,.407,.249,.2000.
. 6.. Maeda,.H.,.et.al.,.Tumor.vascular.permeability.and.the.EPR.effect.in.macromolecular.therapeu-
tics:.a.review,. J. Control. Release ,.65,.271,.2000.
. 7.. Gerweck,. L.E.,. and. Seetharaman,. K.,. Cellular. pH. gradient. in. tumor. versus. normal. tissue:.
potential.exploitation.for.the.treatment.of.cancer,. Cancer Res. ,.56,.1194,.1996.
. 8.. Cook,. J.A.,. et. al.,. Oxidative. stress,. redox,. and. the. tumor. microenvironment,. Semin. Radiat.
Oncol. ,.14,.259,.2004.
. 9.. Malmsten,.M.,. Surfactants and polymers in drug delivery ,.Marcel.Dekker,.New.York,.2002.
. 10.. Feynman.R.P.,.There.is.plenty.of.room.at.the.bottom,.paper.presented.at.Annual.Meeting.of.the.
American.Physical.Society,.California.Institute.of.Technology,.December.29,.1959.
. 11.. Dubas,.S.T.,.Kumlangdudsana,.P.,.and.Potiyaraj,.P.,.Layer-by-layer.deposition.of.antimicrobial.
silver.nanoparticles.on.textile.ibers,. Colloids Surf. A , 289,.105,.2006.
. 12.. Navrotsky,. A.,. Nanomaterials. in. the. environment,. agriculture,. and. technology. (NEAT),. J.
Nanoparticle Res. ,.2,.321,.2000.
. 13.. González-Melendi,. P.,. et. al.,. Nanoparticles. as. smart. treatment-delivery. systems. in. plants:.
assessment.of.different.techniques.of.microscopy.for.their.visualization.in.plant.tissues,. Ann.
Bot. ,.101,.187,.2008.
. 14.. Kruis,.F.E.,.Fissan,.H.,.and.Peled,.A.,.Synthesis.of.nanoparticles.in.the.gas.phase.for.electronic,.
optical.and.magnetic.applications—a.review,. J. Aerosol Sci. ,.29,.511,.1998.
. 15.. Choi,.M.J.,.et.al.,.Metal-containing.nanoparticles.and.nano-structured.particles.in.ingermark.
detection,. Forensic Sci. Int. ,.179,.87,.2008.
 
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