Biomedical Engineering Reference
In-Depth Information
TABLE 10.3
Nano/Microibrous.Textures.Used.in.Cardiac.Muscle.Tissue.Engineering
PolymerConcentration/
Composition/Solvent
PolymerType
FiberDiameter
InVitro Studies:CellType
Reference
Extrusion
PGA
13.μm
Neonatal.rat.cardiomyocytes
Bursac.et.al.,.1999
Papadaki.et.al.,.2001
Collagen.type.I
25.mg/ml
DI.water-HCl
(pH.2.5-3.0)
~.<250.nm.(AF)
Rat.embryonic.cardiac.myocytes
Evans.et.al.,.2003
Yost.et.al.,.2004
Electrospinning
PCL
10%.(w/w)
CHL:MeOH.(1:1)
100.nm-5.μm.(RF)
Neonatal.rat.cardiomyocytes
Shin.et.al.,.2004
Ishii.et.al.,.2005
PLLA
Blend.of.PGLA.(90:10)/PLLA
Blend.of.PLGA.(75:25)/PEG-PDLLA
30-50%.(w/w)
DMF
0.9-1.μm.(RF/AF)
Neonatal.rat.cardiomyocytes
Zong.et.al.,.2005
Blend.of.PLGA/gelatin/α-elastin
10%.PLGA:8%.gelatin:.20%.
elastin.(w/v).HFP
380.±.80.nm.(RF)
H9c2.rat.cardiac.myoblasts
Neonatal.rat.bone.marrow.stromal.cells
Li.et.al.,.2006a
Blends.of.PANi/gelatin
3%.(w/v).CPSA-PANi
8%.(w/v).gelatin.
HFP
From.803.±.121.nm.to.
61.±.13nm.(RF)
H9c2.rat.cardiac.myoblasts
Li.et.al.,.2006b
Biodegradable.polyurethane
15%.(w/v)
DCM
2-10.μm.(RF)
Mouse.ESC-derived.cardiomyocytes.
C2C12.skeletal.myoblast.line
HL-1.cardiomyocyte.cell.line
Fromstein.et.al.,.2008
Zhang.et.al.,.2005
Biodegradable.polyurethane
18%.(w/v)
DCM
1.8.±.1.26.μm.(AF)
2.0.±.1.92.μm.(RF)
Neonatal.rat.cardiomyocytes
Rockwood.et.al.,.2008
Blend.of.PHBV/P(L-D,L)LA/PGS
5%.(w/v)
PHBV:P(L-D,L)LA:PGS.
49:49:2.(w/w)
CHL:DMF.(10:1)
1.10-1.25.μm.(AF)
Human.Wharton's.jelly.MSCs
Kenar.et.al.,.2009
Abbreviations: . PGA,. poly(glycolic. acid);. PCL,. poly(ε-caprolactone);. PLLA,. poly(L-lactide);. PGLA,. poly(glycolide-co-lactide);. PLGA,. poly(lactide-co-glycolide);.
PEG,.poly(ethylene.glycol);.PDLLA,.poly(D,L-lactide);.PHBV,.poly(3-hydroxybutyrate-co-3-hydroxyvalerate);.P(L-D,L)LA,.poly(L-D,L-lactic.acid);.PGS,.
poly(glycerol.sebacate);.CHL,.chloroform;.MeOH,.methanol;.DI,.deionized;.DMF,.N,N-dimethyl.formamide;.HFP,.1,1,1,3,3,3-hexaluoro-2-propanol;.DCM,.
dichloromethane;.PANi,.polyaniline.(conductive.polymer).
 
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