Biomedical Engineering Reference
In-Depth Information
TABLE 10.1 (CONTINUED)
Fibrous.Scaffolds.Fabricated.by.Electrospinning.for.Bone.Tissue.Engineering
InVitroStudies:
Cell Type
PolymerType
PolymerConcentration/Composition/Solvent
FiberDiameter
Reference
PHB,.PHBV,.PHB.-.PHBV.
(50:50.w/w)
14%.w/v
CHL
2,300-4,000 nm
SaOS-2.and.L929
Sombatmankhong.
et al.,.2007
Silk.ibroin.(Nang-Lai.and.
DOAE-7.type)
10-40%.(w/v)
85%.FA
217-610.nm.(Nang-Lai)
183-810 nm.(DOAE-7)
MC3T3-E1
Meechaisue.et.al.,.2007
PLA.(L-.and.DL-type)/PEG
8.2%.w/w.(L-type),.5%.w/w.(DL-type),.
26%.w/w.(PEG-PLLA),.26%.w/w.(PEG-PDLLA)
HFP
246.±.79.nm.(L-type)
141.±.39.nm.(DL-type)
171.±.66.nm.(PEG-PLLA)
889.±.446.nm.(PEG-PDLLA)
MC3T3-E1
Badami.et.al.,.2006
Silk/PEO/nHAp/BMP-2
7.86%.(w/v),
silk:PEO.(82:18.w/w)
5.g.nHAP/100.g.silk
3.mg.BMP-2/mg.silk.ibroin
hMSCs
Li.et.al.,.2006
520.±.55.nm
Gelatin/HAp
80:20.(%.w/w)
HFP
200-400 nm
MG63
Kim.et.al.,.2005
PCL-CaCO
3
PCL:CaCO
3
.=.75:25.and.25:75%.w/w
CHL:MeOH.(75:25%.w/w)
760-900 nm
hFOB
Fujihara.et.al.,.2005
Silk.ibroin/PEO
7.5%.w/w
(80/20 w/w).in.H
2
O
700.±.50 nm
Bone.marrow.stromal.
cells.(BMSCs)
Jin.et.al.,.2004
PCL,.gelatin,.PCL/gelatin
Gelatin:.2.5-12.5%.w/v
PCL:.10%.w/v
50:50.blend:.10%.w/v
TFE
Tens.of.nm-1.μm
BMSC
Zhang.et.al.,.2005
PCL
10%.w/w
CHL
400.±.200.nm
BMSC
Yoshimoto.et.al.,.2003
Abbreviations:
BG,.bioactive.glass;.BMSCs,.bone.marrow-derived.mesenchymal.stem.cells;.CECS,.N-carboxyethyl.chitosan;.CHI,.chitosan;.CHL,.chloroform;.COL,.col-
lagen;. DCM,. dichloromethane;. DMF,. N,N-dimethyl. formamide;. DMSO,. dimethyl. sulfoxide;. FA,. formic. acid;. GPMS,. 3-(glycidoxypropyl). trimethoxysilane;.
HAc,.acetic.acid;.HAp,.hydroxyapatite;.hFOB,.human.fetal.osteoblast;.HFP,.1,1,1,3,3,3-hexaluoro-2-propanol;.hMSC,.human.bone.marrow-derived.mesenchy-
mal.stem.cell;.L929,.mouse.ibroblasts;.MeOH,.methanol;.MC3T3-E1,.mouse.calvaria-derived.murine.preosteoblast.cells;.MG63,.human.osteoblasts.cells;.PAN,.
poly(acrylonitrile);.PCL,.poly(ε-caprolactone);.PEG,.poly(ethylene.glycol);.PEO,.poly(ethylene.oxide);.PHB,.poly(hydroxybutyric.acid);.PHBV,.poly(3-hydroxy-
butyric-co-3-hydroxyvaleric.acid);.PLA,.poly(lactic.acid);.PLGA,.poly(lactic.acid-co-glycolic.acid);.RBM,.rat.bone.marrow.cells;.TFA,.triluoroacetic.acid;.TFE,.
2,2,2-triluoroethanol;.β-TCP,.β-tricalcium.phosphate.
