Biomedical Engineering Reference
In-Depth Information
of. important. viral. diseases.. We. have. developed. virus-speciic,. yet. broadly. neutralizing,.
nanoviricides,.using.ligands.speciic.to.certain.viruses,.such.as.HIV,.inluenza,.and.EKC,.
among.others,.as.well.as.broad-spectrum.nanoviricides.that.are.highly.effective.against.
many. distinctly. different. types. of. viruses,. using. ligands. that. mimic. common. virus. cell.
binding.features.
References
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. 2.. Lindenburg,.C.E.,.I..Stolte,.M.W..Langendam,.F..Miedema,.I.G..Williams,.R..Colebunders,.J.N..
Weber,.M..Fisher,.and.R.A..Coutinho..Long-term.follow-up:.no.effect.of.therapeutic.vaccina-
tion.with.HIV-1.p17/p24:Ty.virus-like.particles.on.HIV-1.disease.progression.. Vaccine .20:2343,.
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chronic.hepatitis.B.infection.. Pediatric Infectious Diseases Journal .22:345,.2003.
. 4.. Nevens,.F.,.T..Roskams,.H..Van.Vlierberghe,.Y..Horsmans,.D..Sprengers,.A..Elewaut,.V..Desmet,.
G..Leroux-Roels,.E..Quinaux,.E..Depla,.et.al..A.pilot.study.of.therapeutic.vaccination.with.enve-
lope.protein.E1.in.35.patients.with.chronic.hepatitis.C.. Hepatology .38:1289,.2003.
. 5.. Rappuoli,.R..Bridging.the.knowledge.gaps.in.vaccine.design.. Nature . Biotechnology .25:1361,.2007.
. 6.. Boni,.M.F..Vaccination.and.antigenic.drift.in.inluenza.. Vaccine .26.(Suppl.3):C8,.2008.
. 7.. Treanor,.J..Inluenza.vaccine—outmaneuvering.antigenic.shift.and.drift.. New England Journal of
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. 10.. De.Clerq,.E..Three.decades.of.antiviral.drugs.. Nature Reviews Drug Discovery .6:941,.2007.
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in. adults. and. children—diagnosis,. treatment,. chemoprophylaxis,. and. institutional. outbreak.
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. 15.. De.Clerq,.E..The.design.of.drugs.for.HIV.and.HCV.. Nature Reviews Drug Discovery 6:1001,.
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. 16.. Kwon,.G.S..Polymeric.micelles.for.delivery.of.poorly.water-soluble.compounds.. Critical Reviews
in Therapeutic Drug Carrier Systems .20:357,.2003.
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. 18.. Uchegbu,.I.F..Pharmaceutical.nanotechnology:.polymeric.vesicles.for.drug.and.gene.delivery..
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