Biomedical Engineering Reference
In-Depth Information
CHAPTER
6
M
icrovascular Bed
s
LEARNING OUTCOMES
1.
Contrast capillary physiology versus
arterial and venous physiology
2.
Describe the important structures within a
capillary bed
3.
Examine mass transfer across the capillary
wall
4.
Discuss endothelial cell physiology
5.
Discuss smooth muscle cell physiology
6.
Identify the mechanisms for information
transfer between endothelial cells and
smooth muscle cells
7.
Assess the theories for local control of
blood flow
8.
Model the pressure distribution
throughout microvascular beds
9.
Model the velocity distribution throughout
microvascular beds
10.
Develop the Stokes equation to describe
flow through microvascular beds
11.
Analyze the drag force on particles
immersed within a fluid
12.
Discuss the relevant physiology of the
interstitial space
13.
Formulate a relationship between flow
through the capillary wall and the pressure
within the capillary and the interstitial
space
14.
Compare the hematocrit in capillaries to
larger blood vessels
15.
Describe the Fahraeus-Lindquist effect
16.
Illustrate the plug flow principle in
capillaries
17.
Model the accumulation of species within
the microcirculation
18.
Analyze blood flow within capillaries as a
two-phase fluid
19.
Describe the interactions of blood cells
with the endothelial cell wall
20.
Explain disease conditions that affect
microvascular beds
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