Chemistry Reference
In-Depth Information
32
33
34
O
O
O
O
O
O
S
S
S
35
36
Scheme 12 Spheriphane cage networks with benzene units
R
R
O
R
N
R
O
N
N
O
O
R
R
O
O
O
O
O
O
O
O
N
N
N
Et
Me
Et
Me
Et
Me
R = OMe
37
38
39
40
Scheme 13 Prismatic and spherical cage networks with benzene units
imine bonds [
77
]. In cryptophane-1.1.1 (40), two [1.1.1]orthocyclophane units are
bridged by three -O-CH
2
-O- linkers [
78
]. Cryptophane derivatives have an inner
cavity surrounded by six benzene units and encapsulate various small chemical
species. For example, encapsulation of inert guest molecules, Xe, methane, and H
2
in 40 was confirmed by spectroscopic methods [
79
,
80
]. The shape and size of
cryptophane 3D networks can be tuned by the length of linkers and the substituents
on benzene rings leading to versatile molecular recognition.
