Biology Reference
In-Depth Information
Table 3.1 A summary of newly identified
a
-glucosidase and
a
-amylase inhibitors from natural plants—cont'd
Inhibition
mechanism
No.
Plant
Part used
Inhibitor
Enzyme origin
Method
IC
50
Reference
25
Polyopes
lancifolia
-
Bis(2,3-dibromo-4,5-
dihydroxybenzyl) ether
Yeast
(
S. cerevisiae
)
pNPG
0.098
m
M Competitive
Bacteria (
B.
stearothermophilus
)
pNPG
0.12
m
M-
Rat intestinal
sucrase/maltase
pNPG
1/1.2 mM -
Terpenoids
26
Momordica
charantia
Fruit
Momordicoside M
Rat intestine
pNPG
50
m
M
inhibit
18.63%
-
27
Momordicoside A
Rat intestine
pNPG
50
m
M
inhibit
21.71%
-
28
Pistacia
integerrima
-
Pistagremic acid
Yeast
(
S. cerevisiae
)
pNPG
89.12
m
M-
Rat intestine
pNPG
62.47
m
M
-
29
Pimpinella
candolleana
Aerial
Ursolic acid
-
pNPG
9.7
m
M-
30
Lagerstroemia
speciosa
Leave
Arjunolic acid
Yeast
(
S. cerevisiae
)
pNPG
38.1
m
M-