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Table 3.1 A summary of newly identified a -glucosidase and a -amylase inhibitors from natural plants—cont'd
Inhibition
mechanism
No.
Plant
Part used
Inhibitor
Enzyme origin
Method
IC 50
Reference
25
Polyopes
lancifolia
-
Bis(2,3-dibromo-4,5-
dihydroxybenzyl) ether
Yeast
( S. cerevisiae )
pNPG
0.098 m M Competitive
Kim, The,
Kurihara, and
Kim (2010)
Bacteria ( B.
stearothermophilus )
pNPG
0.12 m M-
Rat intestinal
sucrase/maltase
pNPG
1/1.2 mM -
Terpenoids
26
Momordica
charantia
Fruit
Momordicoside M
Rat intestine
pNPG
50 m M
inhibit
18.63%
-
Nhiem et al.
(2010)
27
Momordicoside A
Rat intestine
pNPG
50 m M
inhibit
21.71%
-
28
Pistacia
integerrima
-
Pistagremic acid
Yeast
( S. cerevisiae )
pNPG
89.12 m M-
Uddin et al.
(2012)
Rat intestine
pNPG
62.47 m M -
29
Pimpinella
candolleana
Aerial
Ursolic acid
-
pNPG
9.7 m M-
Chang and
Kang (2012)
30
Lagerstroemia
speciosa
Leave
Arjunolic acid
Yeast
( S. cerevisiae )
pNPG
38.1 m M-
Hou et al.,
(2009)
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