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In-Depth Information
In the present study, voxels in several predefined regions are selected as fea-
tures according to ACT-R (Adaptive Control of Thought-Rational) theory [15,
16]. As a cognitive architecture, ACT-R assumes that cognition emerges through
the interaction of a set of modules, 8 brain regions are mapped to these specific
modules. In this study, voxels in 5 bilateral brain regions that are related to the
sudoku solving are selected to build our model. The 5 bilateral brain regions
are as followed: lateral inferior prefrontal cortex (PFC) , centered at Talairach
coordinates x =
40, y = 21, z = 21, reflect retrieval of information in declar-
ative module; posterior parietal cortex (PPC) , centered at x =
±
23, y = -64,
z = 34, reflect changes to problem representations in imaginal module; anterior
cingulate cortex (ACC), centered at x =
±
5, y = 10, z = 38, control various
stages of processing and prevent the problem solving state from distracting from
the goal; caudate, centered at x =
±
15, y = 9, z = 2, play an action-selection
role; and fusiform gyrus (FG), centered at x =
±
42, y = -60, z = -8, engage
in visual processing [14, 15, 16]. 748 voxels in these predefined regions were se-
lected including bilateral PFC (5
±
×
5
×
4, i.e., 5 voxels wide, 5 voxels long, and
4 voxels high), bilateral PPC region (5
×
5
×
4), bilateral FG region (5
×
5
×
3), bilateral ACC region (3
×
5
×
4), bilateral caudate region (4
×
4
×
4).
Feature (Value) Extraction
How to extract feature values to build classifier's input vectors is also a key factor
to affect the performance of classification. According to hemodynamic response
function, the BOLD signal changes by cognition increases to arrive at the peak
values after 4-8 seconds from the cognitive stimuli, then decreases gradually, and
the BOLD signal lasts about 12-14 seconds. So how to abstract the characteristic
of BOLD signal change is very important. In general, as depicted in Figure 3,
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0.4
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0.2
0.2
0.1
0.1
a
0
0
-
0.1
-0.1
-2 -1
0
1
2
3
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-2-1012 34 567
(a) Peak value
(b) Change Rate
0.6
0.6
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0.5
0.4
0.4
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0
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-2-1012 34 567
-2 -1 0 1
2 3 4
5
6 7
-0.1
-0.1
(c) Cumulate changes
(d) Each point value change
Fig. 3. Features used to describe BOLD effect
 
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