Biomedical Engineering Reference
In-Depth Information
not possess the bioactive and osteoconductive properties of calcium
orthophosphates [153, 168].
Table 6.3
Major properties of several FDA-approved biodegradable
polymers [152].
Polymer
Thermal
properties
*
(°C)
Tensile modulus
(GРa)
Degradation
time (months)
Polyglycolic acid
(PGA)
t
= 35-40
7.06
6-12 (strength
loss within 3
weeks)
g
t
= 225-230
m
L-polylactic acid
(LPLA)
t
= 60-65
2.7
> 24
g
t
= 173-178
m
D,L-polylactic acid
(DLPLA)
t
= 55-60
amorphous
1.9
12-16
g
85/15 D,L-
polylactic-
t
= 50-55
amorphous
2.0
5-6
g
co
-
glycolic acid
(85/15 DLPLGA)
75/25 D,L-
polylactic-
t
= 50-55
amorphous
2.0
4-5
g
co
-
glycolic acid
(75/25 DLPLGA)
65/35 D,L-
polylactic-
t
= 45-50
amorphous
2.0
3-4
g
co
-
glycolic acid
(65/35 DLPLGA)
50/50 D,L-
polylactic-
t
= 45-50
amorphous
2.0
1-2
g
co
-
glycolic acid
(50/50 DLPLGA)
Poly(ε-
caprolactone)
(PCL)
t
= ( - 60)
- ( - 65)
t
0.4
> 24
g
= 58-63
m
*
t
: glass transition temperature;
t
: melting point.
g
m
Several classifications of the biomedically relevant polymers are
possible. For example, some authors distinguish between synthetic
polymers such as PLA, PGA or their copolymers with PCL and
polymers of biological origin like polysaccharides (starch, alginate,
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